Zanaflex

Zanaflex ® (Tizanidine)

Generic Name: Tizanidine
Brand Name: Zanaflex

Zanaflex treats muscle spasms. It may also be used for other conditions as determined by your doctor.

Zanaflex is a skeletal muscle relaxant. It works by blocking nerves that stimulate muscles to contract.


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Zanaflex is used for:

Treating muscle spasms. It may also be used for other conditions as determined by your doctor.

Zanaflex is a skeletal muscle relaxant. It works by blocking nerves that stimulate muscles to contract.

Do NOT use Zanaflex if:

  • you are allergic to any ingredient in Zanaflex
  • you are taking ciprofloxacin or fluvoxamine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Zanaflex :

Some medical conditions may interact with Zanaflex . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have liver or kidney problems or prostate problems

Some MEDICINES MAY INTERACT with Zanaflex . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Acyclovir, antiarrhythmics (eg, amiodarone, mexiletine, propafenone), cimetidine, famotidine, fluvoxamine, hormonal contraceptives (eg, birth control pills), quinolone antibiotics (eg, ciprofloxacin), ticlopidine, verapamil, or zileuton because they may increase the risk of Zanaflex ’s side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if this medicine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Zanaflex :

Use Zanaflex as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Zanaflex by mouth.
  • Food can change the way your body absorbs and uses Zanaflex . Be sure to discuss this with your doctor to determine the best way to take your dose, especially when changes to your dose are being considered, or if you are being prescribed a different dose form of Zanaflex (eg, tablets or capsules).
  • Do not stop taking Zanaflex suddenly. If Zanaflex is stopped, the dose should be reduced slowly to prevent symptoms of withdrawal, including high blood pressure, fast heartbeat, tremor, anxiety, and muscle tension.
  • If you miss a dose of Zanaflex , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Zanaflex .

Important safety information:

  • Zanaflex may cause drowsiness, dizziness, lightheadedness, or fainting. These effects may be worse if you take it with alcohol or certain medicines. Use Zanaflex with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Zanaflex ; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Zanaflex may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
  • Tell your doctor or dentist that you take Zanaflex before you receive any medical or dental care, emergency care, or surgery.
  • Do not take more than the recommended dose or use for longer than prescribed without checking with your doctor.
  • Lab tests, such as liver tests, may be performed while you use Zanaflex . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Zanaflex with caution in the ELDERLY; they may be more sensitive to its effects.
  • Zanaflex should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: It is not known if Zanaflex can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Zanaflex while you are pregnant. It is not known if Zanaflex is found in breast milk. If you are or will be breast-feeding while you use Zanaflex , check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Zanaflex :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; dizziness; drowsiness; dry mouth; flushing; tiredness; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); change in emotions, mood, or behavior; hallucinations; increased muscle spasms; muscle weakness; slow heartbeat; trouble urinating or lack of bladder control; urinary tract infection; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include fainting; loss of consciousness; severe drowsiness; trouble breathing.

Proper storage of Zanaflex :

Store Zanaflex at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Zanaflex out of the reach of children and away from pets.

General information:

  • If you have any questions about Zanaflex , please talk with your doctor, pharmacist, or other health care provider.
  • Zanaflex is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Zanaflex . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 7, 2007
Database Edition 07.4.1.002
Copyright © 2007 Wolters Kluwer Health, Inc.

 

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Tramadol

Ultram ® (Tramadol)

Generic Name: Tramadol Tablets (TRA-ma-dole)
Brand Name: Ultram

Ultram is used for treating moderate to moderately severe pain. Ultram is an analgesic. It works in certain areas of the brain and nervous system to decrease pain.


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Ultram is used for:

Treating moderate to moderately severe pain.

Ultram is an analgesic. It works in certain areas of the brain and nervous system to decrease pain.

Do NOT use Ultram if:

  • you are allergic to any ingredient in Ultram
  • you have severe diarrhea due to taking an antibiotic
  • you are intoxicated with alcohol, other opioids or narcotics (eg, morphine, codeine), sedatives or sleeping medicines (eg, temazepam, zolpidem), or other medicines
  • you are taking nefazodone, carbamazepine, or sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Ultram :

Some medical conditions may interact with Ultram . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription (especially depression medicines) or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you are allergic to codeine, a codeine-related medicine (eg, hydrocodone, dihydrocodeine, oxycodone), morphine, or a morphine-related medicine (eg, hydromorphone)
  • if you have a history of alcohol abuse, substance abuse, or suicidal thoughts or behaviors
  • if you have or recently have had any head injury, brain injury or tumor, increased pressure in the brain, or infection of the brain or nervous system
  • if you have a history of stomach or intestinal problems, asthma or other lung or breathing problems, epilepsy, seizures, or chronic inflammation or ulceration of the bowels
  • if you have had recent abdominal surgery
  • if you have heart problems, liver problems (eg, hepatitis), kidney problems, thyroid problems, enlargement of the prostate gland, or urinary problems

Some MEDICINES MAY INTERACT with Ultram . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Carbamazepine because it may decrease Ultram ’s effectiveness and increase the risk of seizures
  • Certain medicines for mental or mood disorders (eg, olanzapine, haloperidol), cyclobenzaprine, isoniazid, other opioid pain medicine (eg, codeine, hydrocodone), phenothiazines (eg, promethazine), sleeping medicines (eg, zolpidem), sodium oxybate (GHB), tricyclic antidepressants (amitriptyline), or weight loss medicines (eg, phentermine) because side effects, including excessive drowsiness, trouble breathing, liver problems, or seizures, may be increased
  • Furazolidone, monoamine oxidase (MAO) inhibitors (eg, phenelzine), nefazodone, selegiline, or selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine) because they may cause serious and sometimes fatal reactions, including restlessness, fever, excessive sweating, confusion, twitching, and seizures
  • Oral anticoagulants (eg, warfarin) because its side effects, including bleeding, may be increased by Ultram
  • Digoxin because the risk of side effects, including nausea, vomiting, or slow heartbeat, may be increased by Ultram

This may not be a complete list of all interactions that may occur. Ask your health care provider if Ultram may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Ultram :

Use Ultram as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Ultram by mouth with or without food.
  • If you miss a dose of Ultram , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Ultram .

Important safety information:

  • Ultram may cause drowsiness and dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Ultram with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Ultram ; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Ultram may cause dizziness; alcohol, hot weather, exercise, or fever may increase this effect. To prevent it, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of this effect.
  • Tell your doctor or dentist that you take Ultram before you receive any medical or dental care, emergency care, or surgery.
  • Use Ultram with caution in the ELDERLY; they may be more sensitive to its effects.
  • Ultram should not be used in CHILDREN younger than 16 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Ultram has been shown to cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Ultram while you are pregnant. Ultram is found in breast milk. Do not breast-feed while taking Ultram .

When used for long periods of time or at high doses, Ultram may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Ultram stops working well. Do not take more than prescribed.

Some people who use Ultram for a long time without a break may develop a physical need to continue taking it. This is known as physical DEPENDENCE. If you suddenly stop taking Ultram , you may experience WITHDRAWAL symptoms including anxiety; diarrhea; fever, runny nose, or sneezing; goose bumps and abnormal skin sensations; nausea; vomiting; pain; rigid muscles; rapid heartbeat; seeing, hearing or feeling things that are not there; shivering or tremors; sweating; and trouble sleeping.

Possible side effects of Ultram :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; increased sweating; loss of appetite; nausea.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation; fainting; fever; incoordination; muscle stiffness or tremor; seizures.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include bluish skin; cold clammy skin; difficult or slow breathing; drowsiness leading to unresponsiveness or coma; excessive sweating; loss of function in the heart and lungs; nausea and vomiting; pinpoint pupils; seizures; stomach or intestinal pain.

Proper storage of Ultram :

Store Ultram at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Ultram out of the reach of children and away from pets.

General information:

  • If you have any questions about Ultram , please talk with your doctor, pharmacist, or other health care provider.
  • Ultram is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Ultram . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 7, 2007
Database Edition 07.4.1.002
Copyright © 2007 Wolters Kluwer Health, Inc.

 

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Ultracet

Ultracet ® (Acetaminophen/Tramadol)

Generic Name: Acetaminophen/Tramadol
Brand Name: Ultracet

Ultracet (Acetaminophen/Tramadol) is used for short-term treatment (5 days or less) of pain.


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Ultracet is used for:

Short-term treatment (5 days or less) of pain.

Ultracet is an analgesic combination. It works in certain areas of the brain and nervous system to decrease pain. The combination may provide better pain relief than either medicine alone.

Do NOT use Ultracet if:

  • you are allergic to any ingredient in Ultracet or any other codeine or morphine related medicine (eg, codeine, oxycodone, hydrocodone, dihydrocodeine, hydromorphone)
  • you have severe diarrhea due to taking an antibiotic
  • you are intoxicated with alcohol, other opioids or narcotics (eg, morphine, codeine), sedatives or sleeping medicines (eg, temazepam, zolpidem), or other medicines
  • you are taking nefazodone or carbamazepine
  • you have liver problems
  • you are taking any other medicine containing tramadol or acetaminophen

Contact your doctor or health care provider right away if any of these apply to you.

Before using Ultracet :

Some medical conditions may interact with Ultracet . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription (especially depression medicines) or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of alcoholism, substance abuse, or if you consume more than 3 alcoholic drinks per day
  • if you have considered or attempted suicide
  • if you have or recently have had any head injury, brain injury or tumor, increased pressure in the brain, infection of the brain or nervous system, epilepsy, or seizures
  • if you have asthma or other lung or breathing problems
  • if you have or have a history of stomach or intestinal problems, chronic inflammation or ulceration of the bowel, or if you have had recent abdominal surgery
  • if you have heart problems, liver problems (eg, hepatitis), kidney problems, thyroid problems, enlargement of the prostate gland, or urinary problems

Some MEDICINES MAY INTERACT with Ultracet . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Carbamazepine because the effectiveness of Ultracet may be decreased and the risk of seizures may be increased
  • Certain medicines for mental or mood disorders (eg, olanzapine, haloperidol), cyclobenzaprine, isoniazid, other opioid pain medicine (eg, codeine, hydrocodone), phenothiazines (eg, promethazine), sleeping medicines (eg, zolpidem), tricyclic antidepressants (amitriptyline), or weight loss medicines (eg, phentermine) because side effects, including excessive drowsiness, trouble breathing, liver problems, or seizures may be increased
  • Linezolid, monoamine oxidase (MAO) inhibitors (eg, phenelzine), nefazodone, selegiline, or SSRIs (eg, fluoxetine) because they may cause serious and sometimes fatal reactions including restlessness, fever, excessive sweating, confusion, twitching, and seizures
  • Oral anticoagulants (eg, warfarin) because side effects, including bleeding, may be increased by Ultracet
  • Digoxin because the risk of side effects, including nausea, vomiting, or slow heartbeat, may be increased by Ultracet

This may not be a complete list of all interactions that may occur. Ask your health care provider if Ultracet may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Ultracet :

Use Ultracet as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Ultracet by mouth with or without food.
  • Do not use Ultracet for more than 5 days unless advised to do so by your doctor.
  • Do not take more than 8 tablets per day. Do not take more than 4 tablets per day if you have kidney problems.
  • If you miss a dose of Ultracet , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use this medicine.

Important safety information:

  • Ultracet may cause drowsiness and dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Ultracet with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Ultracet ; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Ultracet may cause dizziness; alcohol, hot weather, exercise, or fever may increase this effect. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of this effect.
  • Tell your doctor or dentist that you take Ultracet before you receive any medical or dental care, emergency care, or surgery.
  • Ultracet has acetaminophen in it. Before you start any new medicine, check the label to see if it has acetaminophen in it too. If it does or if you are not sure, check with your doctor or pharmacist.
  • Talk to your doctor before you take Ultracet if you drink more than 3 drinks with alcohol per day. Ultracet may cause stomach bleeding. Your risk may be greater if you drink alcohol while you are using Ultracet .
  • Use Ultracet with caution in the ELDERLY; they may be more sensitive to its effects.
  • Ultracet should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Ultracet has been shown to cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Ultracet while you are pregnant. Ultracet is found in breast milk. Do not breast-feed while taking this medicine.

When used for long periods of time or at high doses, Ultracet may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Ultracet stops working well. Do not take more than prescribed.

Some people who use Ultracet for a long time without a break may develop a physical need to continue taking it. This is known as physical DEPENDENCE. If you suddenly stop taking Ultracet , you may experience WITHDRAWAL symptoms including anxiety; diarrhea; fever, runny nose, or sneezing; goose bumps and abnormal skin sensations; nausea and vomiting; pain; rigid muscles; seeing, hearing, or feeling things that are not there; shivering or tremors; sweating; and trouble sleeping.

Possible side effects of Ultracet :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; increased sweating; loss of appetite; nausea.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe seizures (convulsions).

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include bluish skin; cold clammy skin; difficult or slow breathing; drowsiness leading to unresponsiveness or coma; excessive sweating; loss of function in the heart and lungs; nausea and vomiting; pinpoint pupils; seizure (convulsions); stomach or intestinal pain.

Proper storage of Ultracet :

Store Ultracet at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Ultracet out of the reach of children and away from pets.

General information:

  • If you have any questions about Ultracet , please talk with your doctor, pharmacist, or other health care provider.
  • Ultracet is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Ultracet . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 7, 2007
Database Edition 07.4.1.002
Copyright © 2007 Wolters Kluwer Health, Inc.

 

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Carisoprodol

Soma ® (Carisoprodol)

Generic Name: Carisoprodol Tablets
Brand Name: Soma

Soma (Carisoprodol) is a muscle relaxant, used to relieve the pain and stiffness of muscle spasms.


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Soma is used for:

Treating discomfort associated with certain painful muscle conditions. It is usually used along with rest and physical therapy.

Soma is a skeletal muscle relaxant. It works in the brain and spinal cord to relax the muscles. It also causes drowsiness.

Do NOT use Soma if:

  • you are allergic to any ingredient in Soma or to similar medicines (eg, meprobamate)
  • you have the blood disorder porphyria
  • you take sodium oxybate (GHB) or meprobamate

Contact your doctor or health care provider right away if any of these apply to you.

Before using Soma :

Some medical conditions may interact with Soma . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, plan to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines or other substances
  • if you have a history of kidney or liver problems, prostate problems, or seizures
  • if you have a history of alcohol or other substance abuse or dependence

Some MEDICINES MAY INTERACT with Soma . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Sodium oxybate (GHB) because severe drowsiness and prolonged sleep may occur
  • Meprobamate because it may increase the risk of Soma ’s side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Soma may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Soma :

Use Soma as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Soma by mouth with or without food.
  • If you miss a dose of Soma , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Soma .

Important safety information:

  • Soma may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Soma with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not drink alcohol while you are using Soma .
  • Check with your doctor before you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Soma ; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Soma may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
  • Do not take more than the recommended dose or use Soma for longer than 2 to 3 weeks without checking with your doctor.
  • Rarely, some patients have experienced an unexpected reaction within minutes or hours after taking this medicine. Contact your doctor or seek medical care right away if you develop severe weakness, paralysis of the arms or legs, severe dizziness, loss of coordination, vision changes (eg, loss of vision, double vision), joint pain, or mental or mood changes (eg, agitation, confusion, disorientation).
  • Use Soma with caution in Asian patients; they may be more sensitive to its effects.
  • Soma should not be used in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY AND BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Soma while you are pregnant. Soma is found in breast milk. If you are or will be breast-feeding while you use Soma , check with your doctor. Discuss any possible risks to your baby.

Some people who use Soma for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction. If you stop taking Soma suddenly, you may have WITHDRAWAL symptoms. These may include stomach cramps, trouble sleeping, headache, nausea, or seizure.

Possible side effects of Soma :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; drowsiness; headache; lightheadedness; nausea; upset stomach; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; hoarseness); agitation; confusion; disorientation; eye pain or irritation; fainting; fast or irregular heartbeat; fever; joint pain; loss of coordination; mood or mental changes; paralysis in the arms and legs; seizures; severe or persistent dizziness; severe weakness; tremors; vision changes (eg, loss of vision, double vision).

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include confusion; fast heartbeat; hallucinations; loss of consciousness; loss of coordination; rigid muscles; seizures; severe dizziness or drowsiness; slow or irregular breathing; vision problems.

Proper storage of Soma :

Store Soma at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Soma out of the reach of children and away from pets.

General information:

  • If you have any questions about Soma , please talk with your doctor, pharmacist, or other health care provider.
  • Soma is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Soma . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 7, 2007
Database Edition 07.4.1.002
Copyright © 2007 Wolters Kluwer Health, Inc.

 

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Skelaxin

Skelaxin ® (Metaxalone)

Generic Name: Metaxalone
Brand Name: Skelaxin

Skelaxin treatins discomfort associated with acute painful muscle conditions along with rest, physical therapy, or other measures.

Skelaxin is a muscle relaxant. It works in the brain to help relax the muscles.


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Skelaxin is used for:

Treating discomfort associated with acute painful muscle conditions along with rest, physical therapy, or other measures.

Skelaxin is a muscle relaxant. It works in the brain to help relax the muscles.

Do NOT use Skelaxin if:

  • you are allergic to any ingredient in Skelaxin
  • you have a known tendency to drug-induced, hemolytic, or other anemias
  • you have severe liver or kidney problems
  • you are taking sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Skelaxin :

Some medical conditions may interact with Skelaxin . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have an enlarged prostate gland, liver or kidney problems, or the blood disease porphyria

Some MEDICINES MAY INTERACT with Skelaxin . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Sodium oxybate (GHB) because an increase in sleep duration and a decrease in the ability to breath are likely to occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Skelaxin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Skelaxin :

Use Skelaxin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Skelaxin by mouth with or without food. Taking it with food may increase the risk of drowsiness or dizziness.
  • If you miss a dose of Skelaxin and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Skelaxin .

Important safety information:

  • Skelaxin may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Skelaxin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Talk with your doctor before you alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Skelaxin ; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Diabetes patients - Skelaxin may cause the results of some tests for urine glucose to be wrong. Ask your doctor before you change your diet or the dose of your diabetes medicine.
  • Lab tests, including liver function, may be performed while you use Skelaxin . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Skelaxin with caution in the ELDERLY; they may be more sensitive to its effects, especially drowsiness or dizziness.
  • Skelaxin should not be used in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Skelaxin while you are pregnant. It is not known if Skelaxin is found in breast milk. Do not breast-feed while taking Skelaxin .

Possible side effects of Skelaxin :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; drowsiness; headache; irritability; nausea; nervousness; upset stomach; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fever, chills, or sore throat; unusual or severe tiredness or weakness; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of Skelaxin :

Store Skelaxin at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Skelaxin out of the reach of children and away from pets.

General information:

  • If you have any questions about Skelaxin , please talk with your doctor, pharmacist, or other health care provider.
  • Skelaxin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Skelaxin . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 7, 2007
Database Edition 07.4.1.002
Copyright © 2007 Wolters Kluwer Health, Inc.

 

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Flexeril

 

Flexeril ® (Cyclobenzaprine)

Generic Name: Cyclobenzaprine Tablets
Brand Name: Flexeril

Flexeril treats muscle spasms caused by painful muscle conditions. It should be used along with rest and physical therapy. It may also be used for other conditions as determined by your doctor.


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Flexeril is used for:

Treating muscle spasms caused by painful muscle conditions. It should be used along with rest and physical therapy. It may also be used for other conditions as determined by your doctor.

Flexeril is a tricyclic muscle relaxant. It works in parts of the brain and nervous system to help reduce muscle spasms.

Do NOT use Flexeril if:

  • you are allergic to any ingredient in Flexeril
  • you have an overactive thyroid, moderate to severe liver problems, certain heart problems (eg, irregular heartbeat, congestive heart failure, heart block, conduction problems), or if you have recently had a heart attack
  • you are taking or have taken a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) in the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Flexeril :

Some medical conditions may interact with Flexeril . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of liver problems, heart problems, cerebral palsy, brain or spinal cord disease, or stroke
  • if you have a history of glaucoma, increased pressure in the eye, or trouble urinating

Some MEDICINES MAY INTERACT with Flexeril . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • MAOIs (eg, phenelzine) because serious, sometimes fatal reactions, including high fever and severe seizures, may occur
  • Tramadol because the risk of seizures may be increased
  • Droperidol, fluoxetine, or rasagiline because severe heart problems, including irregular heartbeat, may occur
  • Anticholinergics (eg, methscopolamine, benztropine), barbiturates (eg, phenobarbital), cimetidine, fluconazole, fluvoxamine, mibefradil, naproxen, or phenothiazines (eg, chlorpromazine) because they may increase the risk of Flexeril ’s side effects
  • Carbamazepine because it may decrease Flexeril ’s effectiveness or increase the risk of Flexeril ’s side effects
  • Guanethidine or guanfacine because their effectiveness may be decreased by Flexeril
  • Sympathomimetics (eg, albuterol, epinephrine, phenylephrine) because their effectiveness may be decreased or the risk of their side effects may be increased by Flexeril

This may not be a complete list of all interactions that may occur. Ask your health care provider if Flexeril may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Flexeril :

Use Flexeril as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Flexeril by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • Eating grapefruit or drinking grapefruit juice may increase the risk of Flexeril ’s side effects. Talk with your doctor before including grapefruit or grapefruit juice in your diet.
  • Do not suddenly stop taking Flexeril without checking with your doctor.
  • If you miss a dose of Flexeril , take it as soon as possible. If it is almost time for your next dose, skip the missed dose. Go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Flexeril .

Important safety information:

  • Flexeril may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Flexeril with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Flexeril ; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Do NOT take more than the recommended dose or use for longer than 2 to 3 weeks without checking with your doctor.
  • If your symptoms (eg, pain, tenderness, decreased range of motion) do not get better within 2 to 3 weeks or if they get worse, contact your doctor.
  • Do not become overheated in hot weather or while you are being active; heatstroke may occur.
  • If you experience dry mouth, use sugarless candy or gum, or melt bits of ice in your mouth. If dry mouth continues for more than 2 weeks, contact your dentist or doctor.
  • Use Flexeril with extreme caution in the ELDERLY; they may be more sensitive to its effects, especially confusion, hallucinations, and fast or irregular heartbeat.
  • Flexeril should be used with extreme caution in CHILDREN younger than 15 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Flexeril while you are pregnant. It is not known if Flexeril is found in breast milk. If you are or will be breast-feeding while you use Flexeril , check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Flexeril :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; dry mouth; fatigue; nausea; nervousness; stomach pain or upset.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; confusion; fainting; fast or irregular heartbeat; mental or mood changes; numbness of an arm or a leg; one-sided weakness; seizures; sudden severe stomach pain; severe dizziness or vomiting; speech or vision problems; trouble urinating; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include agitation; chest pain; coma; confusion; fast or irregular heartbeat; loss of coordination; hallucinations; seizures; severe drowsiness, dizziness, or headache; slurred speech; tremor; vomiting.

Proper storage of Flexeril :

Store Flexeril at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Flexeril out of the reach of children and away from pets.

General information:

  • If you have any questions about Flexeril , please talk with your doctor, pharmacist, or other health care provider.
  • Flexeril is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Flexeril . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 7, 2007
Database Edition 07.4.1.002
Copyright © 2007 Wolters Kluwer Health, Inc.

 

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Fioricet

Fioricet ® (Butalbital)

Generic Name: Butalbital
Brand Names: Fioricet

Fioricet, a strong, non-narcotic pain reliever and relaxant, is prescribed for the relief of tension headache symptoms caused by muscle contractions in the head, neck, and shoulder area. It combines a sedative barbiturate (butalbital), a non-aspirin pain reliever (acetaminophen), and caffeine.


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Why is Fioricet prescribed?

Fioricet, a strong, non-narcotic pain reliever and relaxant, is prescribed for the relief of tension headache symptoms caused by muscle contractions in the head, neck, and shoulder area. It combines a sedative barbiturate (butalbital), a non-aspirin pain reliever (acetaminophen), and caffeine.

Most important fact about Fioricet

Mental and physical dependence can occur with the use of barbiturates such as butalbital when these drugs are taken in higher than recommended doses over long periods of time.

How should you take Fioricet?

Take Fioricet exactly as prescribed. Do not increase the amount you take without your doctor’s approval.

–If you miss a dose…

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time.

–Storage instructions…

Store at room temperature in a tight, light-resistant container.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Fioricet.

  • More common side effects may include:
    Abdominal pain, dizziness, drowsiness, intoxicated feeling, light-headedness, nausea, sedation, shortness of breath, vomiting

Why should Fioricet not be prescribed?

If you are sensitive to or have ever had an allergic reaction to barbiturates, acetaminophen, or caffeine, you should not take Fioricet. Make sure that your doctor is aware of any drug reactions that you have experienced.

Unless you are directed to do so by your doctor, do not take Fioricet if you have porphyria (an inherited metabolic disorder affecting the liver or bone marrow).

Special warnings about Fioricet

Fioricet may cause you to become drowsy or less alert; therefore, driving or operating dangerous machinery or participating in any hazardous activity that requires full mental alertness is not recommended until you know your response to Fioricet.

If you are being treated for severe depression or have a history of severe depression or drug abuse, consult with your doctor before taking Fioricet.

Use Fioricet with caution if you are elderly or in a weakened condition, if you have liver or kidney problems, or if you have severe abdominal trouble.

Possible food and drug interactions when taking Fioricet

Butalbital slows the central nervous system (CNS) and intensifies the effects of alcohol and other CNS depressants. Use of alcohol with Fioricet may also cause overdose symptoms. Avoid alcoholic beverages while taking Fioricet.

If Fioricet is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Fioricet with the following:

Antihistamines such as Benadryl
Drugs known as monoamine oxidase inhibitors, including the antidepressants Nardil and Parnate
Drugs to treat depression such as Elavil
Major tranquilizers such as Haldol and Thorazine
Muscle relaxants such as Flexeril
Narcotic pain relievers such as Darvon
Sleep aids such as Halcion
Tranquilizers such as Xanax and Valium

Special information if you are pregnant or breastfeeding

If you are pregnant or plan to become pregnant, inform your doctor immediately. Fioricet can affect a developing baby. It also appears in breast milk. If Fioricet is essential to your health, your doctor may advise you to discontinue breastfeeding your baby until your treatment is finished.

Recommended dosage

ADULTS

The usual dose of Fioricet is 1 or 2 tablets taken every 4 hours as needed. Do not exceed a total dose of 6 tablets per day.

The usual dose of Esgic-Plus is 1 tablet every 4 hours as needed. Do not take more than 6 tablets a day.

CHILDREN

The safety and effectiveness of Fioricet have not been established in children under 12 years of age.

OLDER ADULTS

Fioricet may cause excitement, depression, and confusion in older people. Therefore, your doctor will prescribe a dose individualized to suit your needs.

Overdosage

Symptoms of Fioricet overdose can be due to its barbiturate or its acetaminophen component.

  • Symptoms of barbiturate poisoning may include:
    Coma, confusion, drowsiness, low blood pressure, shock, slow or troubled breathing

Overdose due to the acetaminophen component of Fioricet may cause kidney and liver damage, blood disorders, or coma due to low blood sugar. Massive doses may cause liver failure.

  • Symptoms of liver damage include:
    Excess perspiration, feeling of bodily discomfort, nausea, vomiting

If you suspect an overdose, seek emergency medical treatment immediately.

 

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Celebrex

Celebrex ® (Celecoxib)

Generic Name: Celecoxib
Brand Name: Celebrex

Celebrex treats rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, juvenile arthritis, menstrual pain, or pain. It is used in familial adenomatous polyposis (FAP) to decrease the number of polyps (growths) in the rectal area. It may also be used for other conditions as determined by your doctor.


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Celebrex is a nonsteroidal anti-inflammatory drug (NSAID). It may cause an increased risk of serious and sometimes fatal heart and blood vessel problems (eg, heart attack, stroke). The risk may be greater if you already have heart problems or if you take Celebrex for a long time. Do not use Celebrex right before or after bypass heart surgery.

Celebrex may cause an increased risk of serious and sometimes fatal stomach ulcers and bleeding. Elderly patients may be at greater risk. This may occur without warning signs.

Celebrex is used for:

Treating rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, juvenile arthritis, menstrual pain, or pain. It is used in familial adenomatous polyposis (FAP) to decrease the number of polyps (growths) in the rectal area. It may also be used for other conditions as determined by your doctor.

Celebrex is a COX-2 inhibitor NSAID. Exactly how it works is not known. It may block certain substances in the body that are linked to inflammation. NSAIDs treat the symptoms of pain and inflammation. They do not treat the disease that causes those symptoms.

Do NOT use Celebrex if:

  • you are allergic to any ingredient in Celebrex
  • you have had a severe allergic reaction (eg, severe rash, hives, trouble breathing, growths in the nose, dizziness) to aspirin, an NSAID (eg, ibuprofen), or a sulfonamide (eg, sulfamethoxazole)
  • you have recently had or will be having bypass heart surgery
  • you have severe liver problems
  • you are in the last 3 months of pregnancy

Contact your doctor or health care provider right away if any of these apply to you.

Before using Celebrex :

Some medical conditions may interact with Celebrex . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal product, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of kidney or liver disease, diabetes, or stomach or bowel problems (eg, bleeding, perforation, ulcers)
  • if you have a history of swelling or fluid buildup, asthma, growths in the nose (nasal polyps), or mouth inflammation
  • if you have a high fever, rash, high blood pressure, blood disorders, bleeding or clotting problems, heart problems (eg, heart failure), or blood vessel disease, or you are at risk for any of these diseases
  • if you have poor health, dehydration or low fluid volume, or low blood sodium levels, you drink alcohol, or you have a history of alcohol abuse

Some MEDICINES MAY INTERACT with Celebrex . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Anticoagulants (eg, warfarin), aspirin, corticosteroids (eg, prednisone), heparin, or selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine) because risk of stomach bleeding may be increased
  • Fluconazole or probenecid because they may increase the risk of Celebrex ’s side effects
  • Cyclosporine, lithium, methotrexate, or quinolones (eg, ciprofloxacin) because the risk of their side effects may be increased by Celebrex
  • Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril) or diuretics (eg, furosemide, hydrochlorothiazide) because their effectiveness may be decreased by Celebrex

This may not be a complete list of all interactions that may occur. Ask your health care provider if Celebrex may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Celebrex :

Use Celebrex as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Celebrex comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Celebrex refilled.
  • Take Celebrex by mouth. It may be taken with food if it upsets your stomach. Taking it with food may not lower the risk of stomach or bowel problems (eg, bleeding, ulcers). Talk with your doctor or pharmacist if you have persistent stomach upset.
  • Some doses of Celebrex should be taken with food. Ask your doctor if you have questions about how to take Celebrex .
  • Take Celebrex with a full glass of water (8 oz/240 mL) as directed by your doctor.
  • Do not lie down for 30 minutes after you take Celebrex .
  • If you miss a dose of Celebrex and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose. Go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about the proper use of Celebrex .

Important safety information:

  • Celebrex may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Celebrex with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Serious stomach ulcers or bleeding can occur with the use of Celebrex . Taking it in high doses, for a long time, smoking, or drinking alcohol increases the risk of these side effects. Taking Celebrex with food will NOT reduce the risk of these effects. Contact your doctor or emergency room at once if you have severe stomach or back pain; black, tarry stools; vomit that looks like blood or coffee grounds; or unusual weight gain or swelling.
  • Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor
  • Celebrex is an NSAID. Before you start any new medicine, check the label to see if it has an NSAID (eg, ibuprofen) in it too. If it does or if you are not sure, check with your doctor or pharmacist.
  • Do not take aspirin while you are using Celebrex unless your doctor tells you to.
  • FAP patients - Celebrex has not been shown to reduce FAP-related cancers or the need for other procedures or surgeries. Continue your usual care while you use Celebrex .
  • Lab tests, including kidney function, complete blood cell counts, blood clotting, and blood pressure, may be performed while you use Celebrex . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Celebrex with caution in the ELDERLY; they may be more sensitive to its effects, especially stomach bleeding and kidney problems.
  • Caution is advised when using Celebrex in CHILDREN who have juvenile rheumatoid arthritis; they may be more sensitive to its effects, especially blood clotting problems.
  • PREGNANCY and BREAST-FEEDING: Celebrex may cause harm to the fetus. Do not use it during the last 3 months of pregnancy. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Celebrex while you are pregnant. Celebrex is found in breast milk. Do not breast-feed while taking Celebrex .

Possible side effects of Celebrex :

All medicines can cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; gas; headache; heartburn; nausea; sore throat; stomach upset; stuffy nose.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; trouble breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody or black, tarry stools; change in the amount of urine produced; chest pain; confusion; dark urine; depression; fainting; fast or irregular heartbeat; fever, chills, or persistent sore throat; hearing loss; mental or mood changes; numbness of an arm or leg; one-sided weakness; red, swollen, blistered, or peeling skin; ringing in the ears; seizures; severe headache or dizziness; severe or persistent stomach pain or nausea; severe vomiting; shortness of breath; sudden or unexplained weight gain; swelling of hands, legs, or feet; unusual bruising or bleeding; unusual joint or muscle pain; unusual tiredness or weakness; vision or speech changes; vomit that looks like coffee grounds; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include decreased urination; loss of consciousness; seizures; severe dizziness or drowsiness; severe nausea or stomach pain; slow or troubled breathing; unusual bleeding or bruising; vomit that looks like coffee grounds.

Proper storage of Celebrex :

Store Celebrex at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Celebrex out of the reach of children and away from pets.

General information:

  • If you have any questions about Celebrex , please talk with your doctor, pharmacist, or other health care provider.
  • Celebrex is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Celebrex . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 7, 2007
Database Edition 07.4.1.002
Copyright © 2007 Wolters Kluwer Health, Inc.

 

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