Zyprexa is an atypical antipsychotic. It may increase the risk of death when used to treat mental problems caused by dementia in elderly patients. Most of the deaths were linked to heart problems or infection. Zyprexa is not approved to treat mental problems caused by dementia

Zyprexa is used for:

Treating schizophrenia or bipolar disorder. It may also be used for other conditions as determined by your doctor.

Zyprexa is an atypical antipsychotic. Exactly how it works is not known. It is thought to affect certain substances in the brain.

Do NOT use Zyprexa if:

• you are allergic to any ingredient in Zyprexa

Contact your doctor or health care provider right away if any of these apply to you.

Before using Zyprexa :

Some medical conditions may interact with Zyprexa . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a history of seizures, heart problems (eg, heart failure; fast, slow, or irregular heartbeat), abnormal electrocardiogram (ECG), heart attack, stroke, blood vessel problems, high blood cholesterol levels, or high or low blood pressure
• if you have a history of liver problems, stomach or bowel problems (eg, decreased muscle movement), enlarged prostate, narrow-angle glaucoma, neuroleptic malignant syndrome (NMS), aspiration pneumonia, or suicidal thoughts or attempts
• if you have Alzheimer disease, dementia, or trouble swallowing
• if you have diabetes or are very overweight, or if a family member has had diabetes
• if you have had high blood prolactin levels or a history of certain types of cancer (eg, breast, pancreas, pituitary), or if you are at risk for breast cancer
• if you are dehydrated, drink alcohol, or smoke, or you will be exposed to high temperatures

Some MEDICINES MAY INTERACT with Zyprexa . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Alpha blockers (eg, doxazosin), diazepam, or medicine for high blood pressure because the risk of low blood pressure and fainting may be increased
• Anticholinergics (eg, scopolamine), fluvoxamine, or lorazepam because they may increase the risk of Zyprexa ’s side effects
• Carbamazepine, HIV protease inhibitors (eg, ritonavir), omeprazole, or rifampin because they may decrease Zyprexa ’s effectiveness
• Dopamine receptor agonists (eg, pramipexole) or levodopa because their effectiveness may be decreased by Zyprexa

This may not be a complete list of all interactions that may occur. Ask your health care provider if Zyprexa may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Zyprexa :

Use Zyprexa as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Zyprexa by mouth with or without food.
• Drinking extra fluids while you are taking Zyprexa is recommended. Check with your doctor for instructions.
• Continue to take Zyprexa even if you feel well. Do not miss any doses.
• If you miss a dose of Zyprexa , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Zyprexa .

Important safety information:

• Zyprexa may cause dizziness, drowsiness, or decreased vision. These effects may be worse if you take it with alcohol or certain medicines. Use Zyprexa with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Do not drink alcohol while you are using Zyprexa .
• Talk with your doctor before you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Zyprexa ; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
• Zyprexa may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
• Do not become overheated in hot weather or while you are being active; heatstroke may occur.
• Zyprexa may raise your blood sugar. High blood sugar may make you feel confused, drowsy, or thirsty. It can also make you flush, breathe faster, or have a fruit-like breath odor. If these symptoms occur, tell your doctor right away.
• Neuroleptic malignant syndrome (NMS) is a possibly fatal syndrome that can be caused by Zyprexa . Symptoms may include fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbeat; and sweating. Contact your doctor at once if you have any of these symptoms.
• Some patients who take Zyprexa may develop muscle movements that they cannot control. This is more likely to happen in elderly patients, especially women. The chance that this will happen or that it will become permanent is greater in those who take Zyprexa in higher doses or for a long time. Muscle problems may also occur after short-term treatment with low doses. Tell your doctor at once if you have muscle problems with your arms; legs; or your tongue, face, mouth, or jaw (eg, tongue sticking out, puffing of cheeks, mouth puckering, chewing movements) while taking Zyprexa .
• Lab tests, including fasting blood sugar levels and liver function, may be performed while you use Zyprexa . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
• Use Zyprexa with caution in the ELDERLY; they may be more sensitive to its effects, especially uncontrolled muscle movements.
• Zyprexa should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Zyprexa while you are pregnant. Zyprexa is found in breast milk. Do not breast-feed while taking Zyprexa .

Possible side effects of Zyprexa :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back or joint pain; constipation; cough; dizziness; drowsiness; dry mouth; increased appetite; indigestion; lightheadedness; numbness or tingling of the skin; restlessness; sore throat; weakness; weight gain.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); abnormal thoughts; chest pain; confusion; decreased urination; fainting; fast, slow, or irregular heartbeat; fever; increased saliva production or drooling; increased sweating; memory loss; menstrual changes; muscle pain, weakness, or stiffness; new or worsening mental or mood changes (eg, depression, hallucinations); seizures; severe or prolonged dizziness or headache; shortness of breath; swelling of the hands, legs, or feet; symptoms of high blood sugar (eg, increased thirst, hunger, urination; unusual weakness); tremor; trouble concentrating, speaking, or swallowing; trouble sitting still; trouble walking or standing; uncontrolled muscle movements (eg, arm or leg movements, twitching of the face or tongue, jerking or twisting); unusual bruising; vision changes; yellowing of the eyes or skin.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include aggression; agitation; chest pain; coma; difficult or slurred speech; fast or irregular heartbeat; seizure; severe drowsiness; slow or shallow breathing; uncontrolled muscle movements.

Proper storage of Zyprexa :

Store Zyprexa at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep Zyprexa out of the reach of children and away from pets.

General information:

• If you have any questions about Zyprexa , please talk with your doctor, pharmacist, or other health care provider.
• Zyprexa is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Zyprexa . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Xanax is used for:

Treating anxiety and panic disorder. It may also be used to treat other conditions as determined by your doctor.

Xanax is a benzodiazepine. It works by slowing down the movement of chemicals in the brain. This results in a reduction in nervous tension (anxiety).

Do NOT use Xanax if:

• you are allergic to any ingredient in Xanax or other benzodiazepines (eg, diazepam)
• you have acute narrow-angle glaucoma, severe liver disease, or a mental state where contact with reality is lost (psychosis)
• you are taking an azole antifungal (eg, itraconazole, ketoconazole), delavirdine, or sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Xanax :

Some medical conditions may interact with Xanax . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, plan to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines or other substances
• if you have glaucoma or a predisposition for glaucoma, liver problems, lung problems or chronic obstructive pulmonary disease (COPD), muscle problems, depression, suicidal tendencies, a blood disorder known as porphyria, or a history of substance abuse or dependence

Some MEDICINES MAY INTERACT with Xanax . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Rifampin or St. John’s wort because the effectiveness of Xanax may be decreased
• Azole antifungals (eg, itraconazole, ketoconazole), cimetidine, clozapine, delavirdine, fluvoxamine, HIV protease inhibitors (eg, ritonavir), fluoxetine, macrolides and ketolides (eg, erythromycin, azithromycin), nefazodone, omeprazole, propoxyphene, sodium oxybate (GHB), or valproic acid because side effects such as increased sedation or heart problems may occur
• Clozapine, hydantoins (eg, phenytoin), or valproic acid because the actions and side effects of these medicines may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Xanax may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Xanax :

Use Xanax as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Xanax may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
• Avoid eating grapefruit or drinking grapefruit juice while you are being treated with Xanax .
• If you miss a dose of Xanax and you are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Xanax .

Important safety information:

• Xanax may cause drowsiness, dizziness, lightheadedness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Xanax . Using Xanax alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
• Avoid drinking alcohol or taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while taking Xanax . Xanax will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.
• Do not smoke while using Xanax . Cigarette smoking decreases blood levels of Xanax . Tell your doctor if you smoke or if you have recently stopped smoking.
• Use Xanax with caution in the ELDERLY because they may be more sensitive to its effects.
• Xanax is not recommended for use in CHILDREN; safety and effectiveness have not been confirmed.
• PREGNANCY and BREAST-FEEDING: Xanax has been shown to cause harm to the human fetus. If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using Xanax during pregnancy. Xanax is excreted in breast milk. Do not breast-feed while taking Xanax .

When used for long periods of time or at high doses, Xanax may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Xanax stops working well. Do not take more than prescribed.

Xanax may be habit-forming and lead to DEPENDENCE if used in high doses or for a long period of time. If you are on long-term or high dosage therapy, you may have WITHDRAWAL symptoms (eg, convulsions, tremor, stomach and muscle cramps, vomiting, sweating) if you suddenly stop taking this medicine. Do not stop therapy abruptly or change dosage without asking your pharmacist or doctor. Discuss overuse with your doctor or pharmacist.

Possible side effects of Xanax :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Changes in appetite; changes in sexual desire; constipation; dizziness; drowsiness; dry mouth; increased saliva production; lightheadedness; tiredness; trouble concentrating; unsteadiness; weight changes.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; decreased urination; fainting; hallucinations; loss of coordination; memory problems; menstrual changes; muscle twitching; new or worsening mental or mood problems (eg, depression, irritability, anxiety); overstimulation; red, swollen blistered, or peeling skin; seizures; severe dizziness; severe or persistent trouble sleeping; suicidal thoughts or actions; trouble speaking (eg, stammering, stuttering); yellowing of the eyes or skin.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include loss of consciousness; loss of coordination; severe confusion; severe drowsiness or deep sleep; slow reflexes.

Proper storage of Xanax :

Store Xanax at room temperature between 68 and 77 degrees F (20 and 25 degrees C) away from heat, moisture, and light. Do not store in the bathroom. Keep Xanax out of the reach of children and away from pets.

General information:

• If you have any questions about Xanax , please talk with your doctor, pharmacist, or other health care provider.
• Xanax is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Xanax . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Valium is used for:

The management of anxiety disorders. It may also be used to treat agitation, shakiness, and hallucinations during alcohol withdrawal and to relieve certain types of muscle pain and other disorders as determined by your doctor.

Valium is a benzodiazepine. It works by slowing down the movement of chemicals in the brain. This results in a reduction in nervous tension (anxiety) and muscle spasm, and also causes sedation.

Do NOT use Valium if:

• you are allergic to any ingredient in Valium
• you have acute narrow-angle glaucoma, severe liver disease, kidney problems, or a mental state in which contact with reality is lost (psychosis)
• you are taking an HIV protease inhibitor (eg, ritonavir) or sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Valium :

Some medical conditions may interact with Valium . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have glaucoma or a predisposition for glaucoma, liver problems, lung problems or chronic obstructive pulmonary disease (COPD), muscle problems, depression, suicidal tendencies, a blood disorder known as porphyria, or a history of alcohol or other substance abuse or dependence

Some MEDICINES MAY INTERACT with this medicine. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Hydantoins (eg, phenytoin), rifampin, or St. John’s wort because they may decrease Valium ’s effectiveness
• Clozapine, diltiazem, disulfiram,HIV protease inhibitors (eg, ritonavir), narcotic pain relievers (eg, morphine, codeine), nefazodone, omeprazole,sodium oxybate (GHB), or valproic acid because side effects such as increased sedation and confusion may occur
• Hydantoins (eg, phenytoin), narcotic pain relievers (eg, morphine, codeine), sodium oxybate (GHB), succinylcholine, or tricyclic antidepressants (eg, amitriptyline) because the risk of their side effects may be increased by Valium

This may not be a complete list of all interactions that may occur. Ask your health care provider if Valium may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Valium :

Use Valium as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Valium by mouth with or without food.
• If you miss a dose of Valium and you are taking it regularly, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Valium .

Important safety information:

• Valium may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Valium with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Valium ; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
• If you are taking Valium for seizures, carry an ID card at all times that says you have seizure disorder and you take Valium .
• Valium should not be used in CHILDREN younger than 6 months old; safety and effectiveness in these children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: Valium may cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using this medicine while you are pregnant. Valium is found in breast milk. Do not breast-feed while using Valium .

When used for long periods of time or at high doses, Valium may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Valium stops working well. Do not take more than prescribed.

Some people who use Valium for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction. If you stop taking Valium suddenly, you may have WITHDRAWAL symptoms. These may include convulsions, tremor, stomach and muscle cramps, vomiting, or sweating. Do not suddenly stop taking Valium without first checking with your doctor.

Possible side effects of Valium :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; dizziness; drowsiness; dry mouth; fatigue; headaches; incoordination; short-term memory loss; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); anxiety; chest pain; difficulty breathing; difficulty sleeping; difficulty speaking; hallucinations; inability to control urination; increased muscle spasms; interrupted breathing; involuntary eye movement; sleep disturbances; stimulation; sudden rage; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include clumsiness; coma; confusion; deep sleep; loss of consciousness; slow reflexes.

Proper storage of Valium :

Store Valium at room temperature, 59 to 86 degrees F (15 to 30 degrees C), in a tight, light-resistant container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Valium out of the reach of children and away from pets.

General information:

• If you have any questions about Valium , please talk with your doctor, pharmacist, or other health care provider.
• Valium is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Valium . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Klonopin is used for:

Controlling certain types of seizures in the treatment of epilepsy and for the treatment of panic disorders. It may also be used for other conditions as determined by your doctor.

Klonopin is a benzodiazepine. It works by increasing the activity of a naturally occurring chemical in the brain.

Do NOT use Klonopin if:

• you are allergic to any ingredient in Klonopin
• you have a severe mental disorder, acute angle glaucoma, or severe liver disease
• you are taking sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Klonopin :

Some medical conditions may interact with Klonopin . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have or have ever had alcoholism, substance abuse or dependence, or if you consume more than 3 alcohol-containing drinks per day
• if you have depression or have ever considered or attempted suicide
• if you have myasthenia gravis (a condition in which the muscles become progressively weakened)
• if you have angle-closure glaucoma, liver or kidney problems, or porphyria
• if you have chronic bronchitis, chronic obstructive pulmonary disease (COPD), emphysema, or other breathing problems

Some MEDICINES MAY INTERACT with Klonopin . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Antifungals (eg, fluconazole), disulfiram, nefazodone, omeprazole, or valproic acid because they may increase the risk of Klonopin ’s side effects
• Sodium oxybate (GHB) because an increase in sleep duration and a decrease in the ability to breathe may occur
• Clozapine because dangerous side effects, such as confusion, sedation, excess salivation, unsteady movements, lightheadedness especially upon standing, difficult or slow breathing, or drowsiness leading to unresponsiveness or coma, may occur
• Rifampin, St. John’s wort, or valproic acid because they may decrease Klonopin ’s effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if Klonopin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Klonopin :

Use Klonopin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Klonopin by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
• Swallow tablet whole with a full glass of water (8 oz/240 mL).
• If you are taking Klonopin for the prevention of seizures, taking Klonopin at the same times each day will help you remember to take it.
• Continue to take Klonopin even if you feel well. Do not miss any doses. Klonopin works best when there is a constant level of Klonopin in your body.
• If you miss a dose of Klonopin and you are taking it regularly, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Klonopin .

Important safety information:

• Klonopin may cause drowsiness, dizziness, lightheadedness, or difficulty with coordination. These effects may be worse if you take it with alcohol or certain medicines. Use Klonopin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Klonopin may cause you to lose consciousness if you have a history of seizures. Use Klonopin with caution. Do not perform tasks that could be unsafe for you or others if you should lose consciousness (eg, driving, swimming, running heavy machinery).
• Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Klonopin ; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
• Carry an ID card at all times that says you take Klonopin if it is used for seizures.
• LAB TESTS, including liver function, blood counts and electrocardiograms, may be performed while you use Klonopin . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
• Klonopin should not be used in CHILDREN younger than 18 years old with panic disorder; safety and effectiveness in these children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: Klonopin may cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Klonopin while you are pregnant. Klonopin is found in breast milk. Do not breast-feed while taking Klonopin .

When used for long periods of time or at high doses, Klonopin may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Klonopin stops working well. Do not take more than prescribed.

When used for longer than a few weeks or at high doses, some people develop a need to continue taking Klonopin . This is known as DEPENDENCE or addiction. If you stop taking Klonopin suddenly, you may have WITHDRAWAL symptoms. These may include abnormal thoughts or behavioral disorder, anxiety, depression, hallucinations, personality changes or loss of contact with reality; convulsions (seizures); insomnia; stomach and muscle cramps; tremor. Do not suddenly stop taking Klonopin . If you need to stop Klonopin , your doctor will lower your dose over time.

Possible side effects of Klonopin :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Bed wetting; clumsiness or unsteadiness; coated tongue; confusion; constipation; depression; dizziness; drowsiness; excessive daytime drowsiness; feeling of a whirling motion; frequent urination at night; headache; increased saliva (spit); lightheadedness; loss of appetite; runny nose; unusual weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); aggressive behavior; attempted suicide; bizarre behavior; chest congestion; excessive upper respiratory tract secretions; hallucinations; hostility; hysteria; interrupted breathing; memory loss; pounding in the chest; shortness of breath; tremor.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include clumsiness; confusion; difficult or slow breathing; dizziness, light-headedness especially upon standing; drowsiness leading to unresponsiveness or coma; loss of consciousness.

Proper storage of Klonopin :

Store Klonopin at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Klonopin out of the reach of children and away from pets.

General information:

• If you have any questions about Klonopin , please talk with your doctor, pharmacist, or other health care provider.
• Klonopin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Klonopin . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

BuSpar is used for:

The short-term relief of anxiety symptoms. It may also be used for other conditions as determined by your doctor.

BuSpar is an antianxiety agent. It is not known exactly how BuSpar works to relieve anxiety. It is believed that it may react with specific chemical receptors in the brain.

Do NOT use BuSpar if:

• you are allergic to any ingredient in BuSpar
• you are taking furazolidone, sodium oxybate (GHB), or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine), or if you have taken an MAOI within the past 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using BuSpar :

Some medical conditions may interact with BuSpar . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a history of alcoholism or substance abuse, or have severe liver or kidney problems

Some MEDICINES MAY INTERACT with BuSpar . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Rifampin because it may decrease BuSpar ’s effectiveness
• Clozapine, diltiazem, HIV protease inhibitors (eg, ritonavir), imidazoles (eg, ketoconazole), macrolides and ketolides (eg, erythromycin, azithromycin), trazodone, or verapamil because they may increase the risk of this medicine’s side effects, such as dizziness, drowsiness, or fatigue
• Clozapine,MAOIs (eg, phenelzine), selective serotonin reuptake inhibitors (eg, fluoxetine), orsodium oxybate (GHB) because the risk of their side effects may be increased by BuSpar
• Furazolidone because it can cause serious, sometimes fatal, high blood pressure

This may not be a complete list of all interactions that may occur. Ask your health care provider if BuSpar may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use BuSpar :

Use BuSpar as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take BuSpar by mouth. Take it consistently, either always with food or always without food.
• Do not eat grapefruit or drink grapefruit juice while you use BuSpar .
• BuSpar is designed to be taken every day to prevent anxiety symptoms. It does not work if it is only taken as needed or only when anxiety symptoms are present.
• Continue to take BuSpar even if you feel well. Do not miss any doses.
• If you miss a dose of BuSpar , take it as soon as possible. If it is almost time for your next dose skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use BuSpar .

Important safety information:

• BuSpar may cause drowsiness, dizziness, blurred vision, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use BuSpar with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Lab tests, including liver function, kidney function, and complete blood cell counts, may be performed while you use BuSpar . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using BuSpar while you are pregnant. It is not known if BuSpar is found in breast milk. Do not breast-feed while taking BuSpar .

Possible side effects of BuSpar :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Anger/hostility; blurred vision; confusion; decreased concentration; depression; diarrhea; dizziness; drowsiness; dry mouth; excitement; fatigue; headache; lightheadedness; nausea; nervousness; numbness; sleeplessness; stomach pain; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); abnormal muscle movements; difficulty moving.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include decreased pupil size; extreme dizziness or drowsiness; nausea; vomiting.

Proper storage of BuSpar :

Store BuSpar at room temperature, between 59 and 86 degrees F (15 and 30 degrees C) in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Avoid storing at temperatures above 86 degrees F (30 degrees C). Keep BuSpar out of the reach of children and away from pets.

General information:

• If you have any questions about BuSpar , please talk with your doctor, pharmacist, or other health care provider.
• BuSpar is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about BuSpar . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Ativan is used for:

Treating anxiety or anxiety associated with symptoms of depression. It may also be used for other conditions as determined by your doctor.

Ativan is a benzodiazepine. It works by slowing down the movement of chemicals in the brain. This results in a reduction in nervous tension (anxiety) and causes little sedation.

Do NOT use Ativan if:

• you are allergic to any ingredient in Ativan
• you have narrow-angle glaucoma, psychosis, or severe liver disease
• you are taking sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Ativan :

Some medical conditions may interact with Ativan . Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you are taking any other medicine that causes drowsiness (eg, narcotics, some antidepressants)
• if you have impaired lung function, chronic obstructive pulmonary disease (COPD), muscle weakness or fatigue, glaucoma, liver problems, blood disorders, depression, or suicidal thoughts
• if you have a history of drug abuse or dependence

Some MEDICINES MAY INTERACT with Ativan . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Hydantoins (eg, phenytoin) or theophyllines because they may decrease Ativan ’s effectiveness
• Clozapine, kava, loxapine, narcotic pain relievers (eg, morphine, codeine), sodium oxybate (GHB), or valproic acid because side effects, such as extreme sedation, slowed breathing, confusion, or memory problems, may occur
• Digoxin, hydantoins (eg, phenytoin), narcotic pain relievers (eg, morphine, codeine), nondepolarizing muscle relaxants (eg, vecuronium), or sodium oxybate (GHB) because the risk of their side effects may be increased by Ativan
• Nondepolarizing muscle relaxants (eg, vecuronium) because they may decrease Ativan ’s effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if Ativan may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Ativan :

Use Ativan as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Ativan by mouth with or without food.
• If you use Ativan regularly and you miss a dose, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised to by your doctor. If more than one dose is missed, contact your doctor or pharmacist.

Ask your health care provider any questions you may have about how to use Ativan .

Important safety information:

• Ativan may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Ativan with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Ativan without first checking with your doctor; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
• Ativan may be habit forming if you take Ativan in high doses or for a long time. Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
• Lab tests may be performed while you use Ativan . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
• Use Ativan with caution in the ELDERLY; they may be more sensitive to its effects.
• PREGNANCY and BREAST-FEEDING: Ativan has been shown to cause harm to the fetus. Do not become pregnant while you are using it. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Ativan while you are pregnant. Ativan is found in breast milk. Do not breast-feed while taking Ativan .

Some people who use Ativan for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction.

If you stop taking Ativan suddenly, you may have WITHDRAWAL symptoms. These may include agitation, anxiety, irritability, occasional seizures, or sleeplessness may occur if Ativan is suddenly stopped. If you need to stop Ativan , your doctor will lower your dose over time.

Possible side effects of Ativan :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Clumsiness; dizziness; drowsiness; headache; lightheadedness; unsteadiness; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); memory loss.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms of overdose may include clumsiness; confusion; deep sleep; loss of consciousness; or slow reflexes.

Proper storage of Ativan :

Store Ativan at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Ativan out of the reach of children and away from pets.

General information:

• If you have any questions about Ativan , please talk with your doctor, pharmacist, or other health care provider.
• Ativan is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Ativan . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.